KCNS1

Across TCGA patient cohorts, KCNS1 protein abundance is significantly associated with the RNA expression of many other genes, with 527 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCNS1-associated genes across cancer lineages are PES1, PPM1F, and ESS2. Each is linked with KCNS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNS1-to-partner and partner-to-KCNS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNS1 versus PES1 in LSCC, with a Pearson correlation of -0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNS1→partner) and Y-score (partner→KCNS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PES1 →	-1.293	-0.546	.008	.002	3	1
LSCC	PPM1F →	-1.583	-0.546	.002	.002	3	1
LSCC	ESS2 →	-0.682	-0.369	.002	.003	3	1
LSCC	HIRA →	-0.688	-0.369	.002	.003	3	1
LSCC	HPS4 →	-0.668	-0.369	.004	.003	3	1
LSCC	SRRD →	-0.497	-0.369	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 527 associations by consensus.

KCNS1 vs PES1 — LSCC

Explore this scatter interactively →