Across TCGA patient cohorts, KCNQ3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,442 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNQ3-associated proteins across cancer lineages are APOE, NOP16, and PLOD2. Each is linked with KCNQ3 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNQ3-to-partner and partner-to-KCNQ3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNQ3→partner) and Y-score (partner→KCNQ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	APOE →	+0.635	+0.485	<.001	.008	3	4
LSCC	NOP16 →	-0.328	-0.926	<.001	<.001	3	4
LSCC	PLOD2 →	+0.782	+0.973	<.001	<.001	3	4
LUAD	PLS3 →	+0.401	+1.100	.007	.001	3	4
GBM	RTN1 →	+0.420	+0.575	<.001	<.001	3	4
CCRCC	ANGPTL2 →	+0.706	+0.571	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,442 associations by consensus.

Exploration

KCNQ3 survival (RNA) · tumor vs normal (RNA) · all KCNQ3 data types