KCNQ2-AS1

Q-omics provides the consensus-scored KCNQ2-AS1 profile across patient tissues and cancer cell-line models. KCNQ2-AS1 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in UVM. Additionally, KCNQ2-AS1 RNA expression shows 10,229 significant gene co-expression associations, with the highest sampling consensus in PCPG. Together, these results highlight UVM, and PCPG as cancer lineages where KCNQ2-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes KCNQ2-AS1 survival associations across molecular data types. KCNQ2-AS1 RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

KCNQ2-AS1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	UVM (108)	view →

This table ranks reproducible KCNQ2-AS1 RNA expression–survival associations across cancer types. High KCNQ2-AS1 expression shows unfavorable associations in UVM, STAD, UCEC, ESCA, ACC and UCS. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for KCNQ2-AS1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	All	0.242	0.775	<.001	108	view →
STAD	DFS	Tertile	II,III,IV	0.365	0.577	<.001	69	view →
UCEC	OS	Tertile	All	0.842	0.932	<.001	42	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	39	view →
ACC	DFS	Tertile	All	0.106	0.580	.018	36	view →
UCS	DFS	Tertile	IV	0.230	0.767	.009	36	view →

Pink = unfavorable, green = favorable. all 12 lineages →

KCNQ2-AS1-UVM (DFS)

Explore this curve interactively →