KCNN4

Across TCGA cell cohorts, KCNN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,323 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNN4-associated GO terms across cancer lineages are Macropinocytosis, Positive regulation of potassium ion transmembrane transport, and Urokinase plasminogen activator signaling pathway. Each is linked with KCNN4 in more than 15 cancer types. Because this analysis shows association rather than direction, both KCNN4-to-partner and partner-to-KCNN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macropinocytosis grouped by KCNN4-low versus KCNN4-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNN4→partner) and Y-score (partner→KCNN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Macropinocytosis →	+0.241	+3.170	.002	<.001	2	16
BREAST	Positive regulation of potassium ion transmembrane transport →	+0.194	+2.101	<.001	<.001	3	14
LIVER	Urokinase plasminogen activator signaling pathway →	+1.527	+4.305	<.001	<.001	3	14
OESOPHAGUS	Regulation of body fluid levels →	+0.080	+2.136	.001	.006	3	14
BREAST	Regulation of coagulation →	+0.149	+1.696	<.001	.008	3	13
BONE	Actin filament capping →	+0.187	+2.697	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,323 associations by consensus.

Macropinocytosis by KCNN4 expression — BLOOD_Myeloma

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