KCNN1

Across TCGA patient cohorts, KCNN1 mutation is significantly associated with the RNA expression of many other genes, with 3,222 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNN1-associated genes across cancer lineages are CBX1P5, MIR6842, and ME3. Each is linked with KCNN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNN1-to-partner and partner-to-KCNN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBX1P5 grouped by KCNN1-low versus KCNN1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNN1→partner) and Y-score (partner→KCNN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CBX1P5 →	+0.067	+4.409	<.001	.004	3	3
OV	MIR6842 →	+0.290	+4.572	<.001	.008	3	2
UCEC	ME3 →	-0.782	-3.459	<.001	.005	3	2
UCEC	CENPU →	+0.866	+2.354	<.001	.003	3	2
UCEC	MRPL39 →	+0.446	+2.332	.003	.003	3	2
UCEC	MCU →	+0.560	+3.354	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,222 associations by consensus.

CBX1P5 by KCNN1 expression — COAD

Explore this box plot interactively →