KCNN1

Across TCGA cell cohorts, KCNN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,423 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KCNN1-associated GO terms across cancer lineages are DNA-templated transcription initiation, Positive regulation of cation transmembrane transport, and Positive regulation of monoatomic ion transmembrane transport. Each is linked with KCNN1 in more than 11 cancer types. Because this analysis shows association rather than direction, both KCNN1-to-partner and partner-to-KCNN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by KCNN1-low versus KCNN1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNN1→partner) and Y-score (partner→KCNN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription initiation →	+0.106	+3.536	<.001	<.001	3	12
STOMACH	Positive regulation of cation transmembrane transport →	-0.166	-0.541	<.001	<.001	3	11
BONE	Positive regulation of monoatomic ion transmembrane transport →	-0.111	-3.196	<.001	<.001	3	11
BONE	Protein-DNA complex organization →	+0.070	+3.174	<.001	<.001	3	11
OVARY	Positive regulation of double-strand break repair →	+0.087	+1.412	<.001	<.001	3	10
BONE	Epigenetic regulation of gene expression →	+0.090	+3.250	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,423 associations by consensus.

DNA-templated transcription initiation by KCNN1 expression — BONE

Explore this box plot interactively →