KCNMB4

Across TCGA patient cohorts, KCNMB4 mutation is significantly associated with the RNA expression of many other genes, with 949 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNMB4-associated genes across cancer lineages are RNU6-650P, RN7SL375P, and RNU6-1150P. Each is linked with KCNMB4 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNMB4-to-partner and partner-to-KCNMB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-650P grouped by KCNMB4-low versus KCNMB4-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNMB4→partner) and Y-score (partner→KCNMB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-650P →	+0.496	+5.038	<.001	.009	3	2
BLCA	RN7SL375P →	+0.246	+5.106	.004	.008	3	2
LUSC	RNU6-1150P →	+0.443	+4.736	<.001	.001	3	2
UCEC	RNA5SP420 →	+0.618	+2.230	<.001	.005	3	2
SKCM	RN7SL454P →	+0.240	+3.838	<.001	.006	3	2
UCEC	MIR3135A →	+0.342	+2.316	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 949 associations by consensus.

RNU6-650P by KCNMB4 expression — BLCA

Explore this box plot interactively →