Across TCGA patient cohorts, KCNMB2 mutation is significantly associated with the RNA expression of many other genes, with 792 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNMB2-associated genes across cancer lineages are RN7SL44P, PKN3, and SMIM4. Each is linked with KCNMB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNMB2-to-partner and partner-to-KCNMB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNMB2→partner) and Y-score (partner→KCNMB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RN7SL44P →	+0.430	+4.533	<.001	.004	3	2
UCEC	PKN3 →	+0.618	+2.617	.003	.005	3	2
UCEC	SMIM4 →	+0.466	+2.364	.003	.003	3	2
UCEC	TSR3 →	+0.468	+2.724	.002	.003	3	2
UCEC	FTL →	+1.121	+3.032	<.001	<.001	3	2
UCEC	NUBP2 →	+0.404	+2.332	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 792 associations by consensus.

Exploration

KCNMB2 survival (RNA) · tumor vs normal (RNA) · all KCNMB2 data types