KCNMB2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCNMB2 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNMB2-associated genes across cancer lineages are mTOR_pS2448, p70-S6K, and PCNA. Each is linked with KCNMB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNMB2-to-partner and partner-to-KCNMB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNMB2→partner) and Y-score (partner→KCNMB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECmTOR_pS2448 →-0.180-2.980.009.03632
UCECp70-S6K →+0.213+1.901.017.03132
UCECPCNA →+0.271+2.999.007.03532
SKCMBeclin →+0.179+3.169.041.01832
UCECeIF4E →+0.198+2.584.044.01131
UCECFOXO3a_pS318_S321 →-0.140-2.312.016.03431
Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration