KCNMB1

Across TCGA pan-cancer cohorts, KCNMB1 mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of KCNMB1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where KCNMB1 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types KCNMB1 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

COAD and LSCC are the cancer types where KCNMB1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KCNMB1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	III,IV	−1.768	<.001	9	view →
LSCC	All	All	+0.503	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

KCNMB1–COAD

Open the COAD breakdown →