KCNMA1

Across TCGA patient cohorts, KCNMA1 mutation is significantly associated with the total protein of many other genes, with 73 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNMA1-associated genes across cancer lineages are FASN, GAPDH, and FoxM1. Each is linked with KCNMA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNMA1-to-partner and partner-to-KCNMA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by KCNMA1-low versus KCNMA1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNMA1→partner) and Y-score (partner→KCNMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FASN →	+0.487	+2.008	.002	.018	3	4
COAD	GAPDH →	+0.485	+2.182	.018	.033	3	4
STAD	FoxM1 →	+0.227	+1.768	.028	.047	3	3
STAD	ACVRL1 →	-0.172	-3.000	.043	.034	3	3
COAD	Caspase-7-cleavedD198 →	+1.264	+2.708	<.001	.003	3	3
STAD	Caveolin-1 →	-0.703	-2.807	.018	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

FASN by KCNMA1 expression — COAD

Explore this box plot interactively →