KCNK9

Across TCGA pan-cancer cohorts, KCNK9 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated KCNK9 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher KCNK9 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KCNK9 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LUAD, SKCM, and STAD are the cancer types where KCNK9 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.053	0.661	<.001	12	view →
SKCM	OS	Median	II,III,IV	0.762	0.282	.015	9	view →
STAD	OS	Median	IV	0.075	0.496	.013	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

KCNK9–LUAD (OS)

Open the LUAD breakdown →