KCNK9

Across TCGA cell cohorts, KCNK9 mutation is significantly associated with the mutation status of many other genes, with 3,599 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNK9-associated genes across cancer lineages are ARAP2, USP37, and TECPR2. Each is linked with KCNK9 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNK9-to-partner and partner-to-KCNK9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARAP2 grouped by KCNK9-low versus KCNK9-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK9→partner) and Y-score (partner→KCNK9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	ARAP2 →	+4.672	+4.672	.001	.001	1	4
OVARY	USP37 →	+5.415	+5.415	.004	.004	1	4
BLOOD_Leukemia	TECPR2 →	+3.050	+3.247	.008	.008	1	4
BLOOD_Leukemia	ABCC6 →	+3.313	+3.430	.005	.005	1	4
LARGE_INTESTINE	MLH3 →	+2.799	+4.635	<.001	<.001	1	4
OVARY	TBC1D32 →	+5.415	+5.415	.004	.004	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,599 associations by consensus.

ARAP2 by KCNK9 expression — OESOPHAGUS

Explore this box plot interactively →