KCNK5

Across TCGA cell cohorts, KCNK5 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KCNK5-associated genes across cancer lineages are FAM205A, IFNG, and MC3R. Each is linked with KCNK5 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK5-to-partner and partner-to-KCNK5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM205A grouped by KCNK5-low versus KCNK5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK5→partner) and Y-score (partner→KCNK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM205A →	+0.025	+4.614	<.001	.002	3	1
SKIN	IFNG →	+0.016	+4.437	<.001	.004	3	1
SKIN	MC3R →	+0.195	+3.884	<.001	.005	3	1
SKIN	OR6X1 →	+0.018	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

FAM205A by KCNK5 expression — LARGE_INTESTINE

Explore this box plot interactively →