KCNK3

Across TCGA cell cohorts, KCNK3 mutation is significantly associated with the drug of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNK3-associated genes across cancer lineages are GSK2276186C, GSK2110183B, and XMD14-99. Each is linked with KCNK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK3-to-partner and partner-to-KCNK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK2276186C grouped by KCNK3-low versus KCNK3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK3→partner) and Y-score (partner→KCNK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK2276186C →	+0.484	+2.871	.027	.021	3	1
LARGE_INTESTINE	GSK2110183B →	+0.736	+2.871	.009	.021	2	2
LARGE_INTESTINE	XMD14-99 →	+0.362	+2.874	.021	.021	3	1
LARGE_INTESTINE	KIN001-236 →	+0.291	+2.874	.033	.021	3	1
LARGE_INTESTINE	BIBF-1120 →	+0.460	+2.874	.036	.021	3	1
LARGE_INTESTINE	Dinaciclib →	+0.554	+2.868	.022	.022	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

GSK2276186C by KCNK3 expression — LARGE_INTESTINE

Explore this box plot interactively →