KCNK2

Across TCGA patient cohorts, KCNK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,343 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KCNK2-associated proteins across cancer lineages are CACNA2D1, FBLN2, and VCAN. Each is linked with KCNK2 in more than 6 cancer types. Because this analysis shows association rather than direction, both KCNK2-to-partner and partner-to-KCNK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNK2 versus CACNA2D1 in COAD, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK2→partner) and Y-score (partner→KCNK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CACNA2D1 →	+0.721	+0.558	<.001	<.001	3	7
COAD	FBLN2 →	+0.638	+0.367	<.001	.001	3	6
COAD	VCAN →	+0.755	+0.400	<.001	<.001	3	6
PDAC	PPM1F →	+0.265	+0.918	<.001	<.001	3	5
BRCA	RPL6 →	-0.385	-0.982	<.001	.001	3	5
COAD	RPL5 →	-0.199	-0.555	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,343 associations by consensus.

KCNK2 vs CACNA2D1 — COAD

Explore this scatter interactively →