KCNK2

Across TCGA patient cohorts, KCNK2 protein abundance is significantly associated with the RNA expression of many other genes, with 207 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNK2-associated genes across cancer lineages are RAB5IF, CCNJ, and PLEKHA1. Each is linked with KCNK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK2-to-partner and partner-to-KCNK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNK2 versus RAB5IF in GBM, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK2→partner) and Y-score (partner→KCNK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAB5IF →	-0.691	-0.376	<.001	.005	3	1
GBM	CCNJ →	+0.455	+0.392	<.001	.003	3	1
GBM	PLEKHA1 →	+0.503	+0.427	<.001	.001	3	1
GBM	CILK1 →	+0.722	+0.430	.003	.002	3	1
GBM	FHL5 →	+0.890	+0.417	.001	.001	3	1
GBM	EIF4G1 →	-0.302	-0.362	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 207 associations by consensus.

KCNK2 vs RAB5IF — GBM

Explore this scatter interactively →