Across TCGA cell cohorts, KCNK18 RNA expression is significantly associated with the go_rna of many other GO terms, with 180 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNK18-associated GO terms across cancer lineages are Regulation of chromatin organization, Positive regulation of fertilization, and Positive regulation of CD8-positive, alpha-beta T cell activation. Each is linked with KCNK18 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK18-to-partner and partner-to-KCNK18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK18→partner) and Y-score (partner→KCNK18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of chromatin organization →	+0.054	+0.009	.003	.005	3	2
LARGE_INTESTINE	Positive regulation of fertilization →	-0.866	-0.009	.002	.004	3	2
LARGE_INTESTINE	Positive regulation of CD8-positive, alpha-beta T cell activation →	+0.164	+0.009	<.001	.003	3	2
LARGE_INTESTINE	Negative regulation of neurogenesis →	+0.058	+0.009	.002	.005	3	2
BONE	Non-proteinogenic amino acid metabolic process →	+0.073	+0.126	.006	.003	3	1
BONE	Internal peptidyl-lysine acetylation →	+0.212	+0.120	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 180 associations by consensus.

Exploration

KCNK18 survival (RNA) · tumor vs normal (RNA) · all KCNK18 data types