KCNK17

Across TCGA cell cohorts, KCNK17 RNA expression is significantly associated with the go_rna of many other GO terms, with 695 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNK17-associated GO terms across cancer lineages are Negative regulation of protein-containing complex assembly, Adenylate cyclase-modulating G protein-coupled receptor signaling pathway, and Adenylate cyclase-activating G protein-coupled receptor signaling pathway. Each is linked with KCNK17 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNK17-to-partner and partner-to-KCNK17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein-containing complex assembly grouped by KCNK17-low versus KCNK17-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK17→partner) and Y-score (partner→KCNK17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of protein-containing complex assembly →	+0.036	+1.467	<.001	<.001	3	3
LUNG_SCLC	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.054	-1.353	<.001	.003	3	3
LUNG_SCLC	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.044	-1.637	.003	.007	3	3
OVARY	Positive regulation of double-strand break repair via homologous recombination →	+0.067	+0.017	<.001	.004	2	4
BREAST	Regulation of ubiquitin-dependent protein catabolic process →	+0.053	+0.055	<.001	<.001	3	3
BREAST	scaRNA localization to Cajal body →	+0.054	+0.030	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 695 associations by consensus.

Negative regulation of protein-containing complex assembly by KCNK17 expression — BLOOD_Leukemia

Explore this box plot interactively →