KCNK13

Across TCGA cell cohorts, KCNK13 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,940 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KCNK13-associated GO terms across cancer lineages are Protein-RNA complex organization, Adenylate cyclase-modulating G protein-coupled receptor signaling pathway, and Positive regulation of stem cell population maintenance. Each is linked with KCNK13 in more than 7 cancer types. Because this analysis shows association rather than direction, both KCNK13-to-partner and partner-to-KCNK13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-RNA complex organization grouped by KCNK13-low versus KCNK13-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK13→partner) and Y-score (partner→KCNK13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein-RNA complex organization →	+0.072	+0.150	<.001	.002	3	7
OVARY	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.070	-0.622	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Positive regulation of stem cell population maintenance →	+0.078	+0.164	<.001	<.001	3	7
STOMACH	Protein-RNA complex assembly →	+0.086	+0.344	<.001	.009	3	7
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.124	+0.292	<.001	.004	3	7
OESOPHAGUS	Aerobic electron transport chain →	+0.109	+0.323	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,940 associations by consensus.

Protein-RNA complex organization by KCNK13 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →