KCNK13

Across TCGA cell cohorts, KCNK13 mutation is significantly associated with the drug of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNK13-associated genes across cancer lineages are NU7441, BPTES, and AZD6738. Each is linked with KCNK13 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK13-to-partner and partner-to-KCNK13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NU7441 grouped by KCNK13-low versus KCNK13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK13→partner) and Y-score (partner→KCNK13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NU7441 →	+0.485	+2.807	.017	.046	3	1
LARGE_INTESTINE	BPTES →	+0.373	+2.871	.028	.021	3	1
LARGE_INTESTINE	AZD6738 →	+0.532	+2.871	.033	.021	3	1
LARGE_INTESTINE	AZD8186 →	+0.564	+2.871	.016	.021	3	1
LARGE_INTESTINE	BMS-345541 →	+0.498	+2.868	.038	.022	2	1
LARGE_INTESTINE	JAK1_8709 →	+0.464	+2.649	.018	.046	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

NU7441 by KCNK13 expression — LARGE_INTESTINE

Explore this box plot interactively →