KCNK10

Across TCGA cell cohorts, KCNK10 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KCNK10-associated genes across cancer lineages are ACOD1, DAO, and FGF6. Each is linked with KCNK10 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNK10-to-partner and partner-to-KCNK10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACOD1 grouped by KCNK10-low versus KCNK10-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNK10→partner) and Y-score (partner→KCNK10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ACOD1 →	+0.006	+4.867	<.001	.009	3	2
OVARY	DAO →	+0.067	+4.263	<.001	.002	3	1
OVARY	FGF6 →	+0.040	+4.222	<.001	.006	3	1
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1
OVARY	CCDC140 →	+0.355	+3.938	<.001	.005	3	1
OVARY	GPR101 →	+0.019	+3.990	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

ACOD1 by KCNK10 expression — BLOOD_Lymphoma

Explore this box plot interactively →