KCNJ9

Across TCGA patient cohorts, KCNJ9 mutation is significantly associated with the RNA expression of many other genes, with 724 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNJ9-associated genes across cancer lineages are RPS29P26, RNA5SP418, and OR5L1. Each is linked with KCNJ9 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ9-to-partner and partner-to-KCNJ9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS29P26 grouped by KCNJ9-low versus KCNJ9-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ9→partner) and Y-score (partner→KCNJ9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPS29P26 →	+0.348	+7.930	<.001	.008	3	2
UCEC	RNA5SP418 →	+0.883	+2.126	<.001	.007	3	2
BRCA	OR5L1 →	+0.039	+7.731	<.001	.009	3	1
BRCA	PRR20A →	+0.024	+8.471	<.001	.005	3	1
BRCA	RNU6-746P →	+0.318	+8.471	<.001	.005	3	1
BRCA	MIR329-2 →	+0.387	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 724 associations by consensus.

RPS29P26 by KCNJ9 expression — LUAD

Explore this box plot interactively →