KCNJ9

Across TCGA cell cohorts, KCNJ9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,572 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KCNJ9-associated GO terms across cancer lineages are Positive regulation of protein localization to nucleus, Alternative mRNA splicing, via spliceosome, and Endosomal transport. Each is linked with KCNJ9 in more than 6 cancer types. Because this analysis shows association rather than direction, both KCNJ9-to-partner and partner-to-KCNJ9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to nucleus grouped by KCNJ9-low versus KCNJ9-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ9→partner) and Y-score (partner→KCNJ9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of protein localization to nucleus →	+0.077	+0.160	<.001	.006	3	7
LUNG_SCLC	Alternative mRNA splicing, via spliceosome →	+0.082	+0.451	<.001	.002	3	7
LUNG_NSCLC_LUAD	Endosomal transport →	+0.038	+0.042	<.001	.002	3	6
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.140	+0.655	<.001	<.001	3	6
LARGE_INTESTINE	Regulation of protein localization to nucleus →	+0.062	+0.109	<.001	.003	3	6
LARGE_INTESTINE	Regulation of syncytium formation by plasma membrane fusion →	+0.051	+0.106	<.001	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,572 associations by consensus.

Positive regulation of protein localization to nucleus by KCNJ9 expression — LARGE_INTESTINE

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