KCNJ8

Across TCGA patient cohorts, KCNJ8 protein abundance is significantly associated with the RNA expression of many other genes, with 461 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KCNJ8-associated genes across cancer lineages are RBP1, PGRMC1, and LILRA1. Each is linked with KCNJ8 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ8-to-partner and partner-to-KCNJ8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNJ8 versus RBP1 in GBM, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ8→partner) and Y-score (partner→KCNJ8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBP1 →	+1.840	+0.763	.007	.007	3	2
PDAC	PGRMC1 →	-0.386	-0.635	.007	.003	3	1
PDAC	LILRA1 →	+0.565	+0.614	<.001	.007	3	1
PDAC	AP1S1 →	-0.642	-0.481	.001	.005	3	1
PDAC	ZNHIT1 →	-0.423	-0.571	<.001	<.001	3	1
PDAC	TMEM176B →	-0.666	-0.616	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 461 associations by consensus.

KCNJ8 vs RBP1 — GBM

Explore this scatter interactively →