KCNJ6

Across TCGA patient cohorts, KCNJ6 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,135 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KCNJ6-associated GO terms across cancer lineages are Axon extension, Dendrite development, and Rac protein signal transduction. Each is linked with KCNJ6 in more than 17 cancer types. Because this analysis shows association rather than direction, both KCNJ6-to-partner and partner-to-KCNJ6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Axon extension grouped by KCNJ6-low versus KCNJ6-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ6→partner) and Y-score (partner→KCNJ6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Axon extension →	+0.050	+0.210	<.001	<.001	3	18
SCLC	Dendrite development →	+0.053	+1.000	<.001	<.001	3	17
SCLC	Rac protein signal transduction →	+0.080	+1.226	.001	.002	2	18
STAD	Positive regulation of Wnt signaling pathway →	+0.060	+0.186	<.001	<.001	3	17
STAD	Regeneration →	+0.052	+0.207	<.001	<.001	3	17
STAD	Regulation of cell size →	+0.052	+0.208	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,135 associations by consensus.

Axon extension by KCNJ6 expression — STAD

Explore this box plot interactively →