KCNJ6

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCNJ6 protein abundance is significantly associated with the RNA expression of many other genes, with 1,272 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNJ6-associated genes across cancer lineages are RASL10A, NEFH, and RASD2. Each is linked with KCNJ6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ6-to-partner and partner-to-KCNJ6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNJ6 versus RASL10A in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ6→partner) and Y-score (partner→KCNJ6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRASL10A →+0.824+0.586.002.00331
GBMNEFH →+0.938+0.642<.001<.00131
GBMRASD2 →+0.510+0.613<.001<.00131
GBMCBX7 →+0.508+0.624.005.00231
GBMSYNGR1 →+0.831+0.615.002.00431
GBMPNPLA5 →+0.344+0.675<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,272 associations by consensus.

KCNJ6 vs RASL10A — GBM

Per-sample scatter of KCNJ6 vs RASL10A in GBM (Pearson r = 0.35).

Explore this scatter interactively →

Exploration