KCNJ6

Across TCGA patient cohorts, KCNJ6 protein abundance is significantly associated with the protein abundance of many other proteins, with 6,977 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KCNJ6-associated proteins across cancer lineages are ARPP21, ARPP21_S33, and ACIN1_S667. Each is linked with KCNJ6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ6-to-partner and partner-to-KCNJ6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNJ6 versus ARPP21 in GBM, with a Pearson correlation of 0.38.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ6→partner) and Y-score (partner→KCNJ6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARPP21 →	+0.833	+0.758	<.001	<.001	3	1
GBM	ARPP21_S33 →	+1.211	+0.746	<.001	<.001	3	1
GBM	ACIN1_S667 →	-0.366	-0.636	<.001	<.001	3	1
GBM	ASH2L →	-0.302	-0.592	.001	.001	3	1
GBM	ACIN1_S729 →	-0.508	-0.744	<.001	<.001	3	1
GBM	ACIN1_S898 →	-0.473	-1.024	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,977 associations by consensus.

KCNJ6 vs ARPP21 — GBM

Explore this scatter interactively →