KCNJ6

Across TCGA cell cohorts, KCNJ6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,471 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KCNJ6-associated GO terms across cancer lineages are Cytoplasmic translation, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with KCNJ6 in more than 7 cancer types. Because this analysis shows association rather than direction, both KCNJ6-to-partner and partner-to-KCNJ6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by KCNJ6-low versus KCNJ6-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ6→partner) and Y-score (partner→KCNJ6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cytoplasmic translation →	+0.052	+0.044	<.001	.001	3	8
SKIN	Negative regulation of myoblast fusion →	+0.103	+0.078	<.001	.002	3	8
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.105	+0.078	<.001	.002	3	8
SKIN	Regulation of syncytium formation by plasma membrane fusion →	+0.056	+0.047	<.001	<.001	3	7
SOFT_TISSUE	Regulation of proteasomal protein catabolic process →	+0.034	+0.647	.001	.003	3	6
SOFT_TISSUE	Response to unfolded protein →	+0.058	+0.755	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,471 associations by consensus.

Cytoplasmic translation by KCNJ6 expression — SKIN

Explore this box plot interactively →