KCNJ5

Across TCGA cell cohorts, KCNJ5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,239 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KCNJ5-associated GO terms across cancer lineages are Regulation of double-strand break repair, Cytoplasmic translation, and Regulation of telomere maintenance via telomerase. Each is linked with KCNJ5 in more than 6 cancer types. Because this analysis shows association rather than direction, both KCNJ5-to-partner and partner-to-KCNJ5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair grouped by KCNJ5-low versus KCNJ5-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ5→partner) and Y-score (partner→KCNJ5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of double-strand break repair →	+0.053	+0.825	.005	.003	3	6
LUNG_NSCLC_LUAD	Cytoplasmic translation →	+0.038	+0.057	<.001	.007	3	6
LARGE_INTESTINE	Regulation of telomere maintenance via telomerase →	+0.037	+0.270	.002	.006	2	7
KIDNEY	Negative regulation of mRNA catabolic process →	+0.044	+0.041	.002	<.001	3	6
KIDNEY	Positive regulation of podosome assembly →	+0.256	+0.047	.004	.001	3	6
OVARY	Regulation of cell cycle G1/S phase transition →	+0.054	+0.514	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,239 associations by consensus.

Regulation of double-strand break repair by KCNJ5 expression — SOFT_TISSUE

Explore this box plot interactively →