KCNJ2

Across TCGA patient cohorts, KCNJ2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,676 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KCNJ2-associated genes across cancer lineages are WDR13, TWNK, and HDAC5. Each is linked with KCNJ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ2-to-partner and partner-to-KCNJ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNJ2 versus WDR13 in GBM, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ2→partner) and Y-score (partner→KCNJ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WDR13 →	-0.516	-0.798	.008	.003	3	1
GBM	TWNK →	-0.456	-0.647	<.001	<.001	3	1
GBM	HDAC5 →	-0.483	-0.650	.007	.004	3	1
GBM	SLC39A7 →	-0.843	-0.730	.005	.003	3	1
GBM	PHF1 →	-1.021	-1.035	.004	<.001	3	1
GBM	LYPLA1 →	+0.576	+0.546	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,676 associations by consensus.

KCNJ2 vs WDR13 — GBM

Explore this scatter interactively →