KCNJ2

Across TCGA cell cohorts, KCNJ2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,997 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNJ2-associated GO terms across cancer lineages are Positive regulation of platelet activation, Positive regulation of actin filament bundle assembly, and Stem cell population maintenance. Each is linked with KCNJ2 in more than 6 cancer types. Because this analysis shows association rather than direction, both KCNJ2-to-partner and partner-to-KCNJ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of platelet activation grouped by KCNJ2-low versus KCNJ2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ2→partner) and Y-score (partner→KCNJ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of platelet activation →	-0.197	-1.061	<.001	.002	3	7
LUNG_SCLC	Positive regulation of actin filament bundle assembly →	+0.059	+0.627	.007	.007	3	6
OESOPHAGUS	Stem cell population maintenance →	+0.061	+0.791	.003	.006	3	6
UPPER_AERODIGESTIVE_TRACT	Nucleotide-sugar metabolic process →	+0.060	+0.788	<.001	<.001	3	5
BLOOD_Leukemia	Paranodal junction assembly →	+0.810	+0.782	<.001	.001	3	5
URINARY_TRACT	Ganglion development →	+0.120	+0.944	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,997 associations by consensus.

Positive regulation of platelet activation by KCNJ2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →