KCNJ2-AS1

Across TCGA pan-cancer cohorts, KCNJ2-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated KCNJ2-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher KCNJ2-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated KCNJ2-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and PAAD show a favorable association.

UCS, PAAD, and BLCA are the cancer types where KCNJ2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	II,III,IV	0.576	0.173	<.001	96	view →
PAAD	OS	Median	All	0.524	0.280	<.001	51	view →
BLCA	OS	Tertile	II,III,IV	0.550	0.719	<.001	50	view →
READ	DFS	Median	All	0.713	0.385	.002	34	view →
DLBC	DFS	Tertile	III,IV	0.130	0.984	.001	31	view →
MESO	OS	Tertile	All	0.867	0.352	.001	30	view →
LUAD	OS	Tertile	II,III,IV	0.780	0.653	.014	26	view →
THCA	OS	Tertile	All	1.000	0.912	.008	20	view →
KIRP	OS	Tertile	All	0.847	0.565	.002	15	view →
LIHC	OS	Median	II,III,IV	0.586	0.306	.008	13	view →
KICH	DFS	Median	III,IV	0.373	1.000	.008	12	view →
UVM	OS	Tertile	III,IV	0.286	0.836	.025	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

KCNJ2-AS1–UCS (DFS)

Open the UCS breakdown →