KCNJ15

Across TCGA pan-cancer cohorts, KCNJ15 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated KCNJ15 data layer compared with 22 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher KCNJ15 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KCNJ15 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

LIHC, UCEC, and GBM are the cancer types where KCNJ15 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	II,III,IV	0.153	0.617	.005	12	view →
UCEC	DFS	Median	All	0.955	0.634	.038	4	view →
GBM	OS	Median	All	0.075	0.416	.011	3	view →
HNSC	DFS	Median	III,IV	1.000	0.653	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

KCNJ15–LIHC (OS)

Open the LIHC breakdown →