KCNJ15

Across TCGA pan-cancer cohorts, KCNJ15 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated KCNJ15 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher KCNJ15 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KCNJ15 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and PDAC are the cancer types where KCNJ15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.940	0.658	.003	31	view →
LUAD	OS	Median	III,IV	0.670	0.211	.004	28	view →
PDAC	DFS	Tertile	II,III,IV	0.549	0.818	.014	6	view →
LSCC	DFS	Median	All	0.552	0.910	.030	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

KCNJ15–CCRCC (DFS)

Open the CCRCC breakdown →