KCNJ15

Across TCGA cell cohorts, KCNJ15 mutation is significantly associated with the RNA expression of many other genes, with 562 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNJ15-associated genes across cancer lineages are MRPL18, PEF1, and KIFBP. Each is linked with KCNJ15 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ15-to-partner and partner-to-KCNJ15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPL18 grouped by KCNJ15-low versus KCNJ15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ15→partner) and Y-score (partner→KCNJ15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MRPL18 →	+0.474	+3.364	.001	.002	3	2
LARGE_INTESTINE	PEF1 →	+0.531	+3.364	.001	.002	3	2
LARGE_INTESTINE	KIFBP →	+0.714	+3.169	<.001	.009	3	2
SKIN	BHMT →	+0.124	+4.131	<.001	<.001	3	1
SKIN	NCBP2L →	+0.024	+2.669	.004	.004	3	1
SKIN	TNP2 →	+0.010	+3.415	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 562 associations by consensus.

MRPL18 by KCNJ15 expression — LARGE_INTESTINE

Explore this box plot interactively →