KCNJ13

Across TCGA patient cohorts, KCNJ13 mutation is significantly associated with the RNA expression of many other genes, with 789 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNJ13-associated genes across cancer lineages are RN7SL143P, MIR449B, and MIR4507. Each is linked with KCNJ13 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ13-to-partner and partner-to-KCNJ13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL143P grouped by KCNJ13-low versus KCNJ13-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ13→partner) and Y-score (partner→KCNJ13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RN7SL143P →	+0.169	+5.925	<.001	.002	3	2
HNSC	MIR449B →	+0.323	+7.954	<.001	.008	3	2
UCEC	MIR4507 →	+0.234	+2.513	.001	.007	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	1
UCEC	PRSS53 →	+0.279	+3.544	.001	.002	3	1
UCEC	TEX30 →	+0.622	+2.230	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 789 associations by consensus.

RN7SL143P by KCNJ13 expression — READ

Explore this box plot interactively →