KCNJ13

Across TCGA cell cohorts, KCNJ13 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,211 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KCNJ13-associated GO terms across cancer lineages are Negative regulation of transcription elongation by RNA polymerase II, Viral transcription, and Subtelomeric heterochromatin formation. Each is linked with KCNJ13 in more than 9 cancer types. Because this analysis shows association rather than direction, both KCNJ13-to-partner and partner-to-KCNJ13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transcription elongation by RNA polymerase II grouped by KCNJ13-low versus KCNJ13-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ13→partner) and Y-score (partner→KCNJ13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription elongation by RNA polymerase II →	+0.101	+0.155	<.001	.004	3	10
BLOOD_Leukemia	Viral transcription →	+0.097	+0.130	<.001	<.001	3	10
LARGE_INTESTINE	Subtelomeric heterochromatin formation →	+0.136	+0.274	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.107	+0.204	<.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Protein targeting to vacuole →	+0.062	+0.157	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.060	+0.160	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,211 associations by consensus.

Negative regulation of transcription elongation by RNA polymerase II by KCNJ13 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →