Across TCGA patient cohorts, KCNJ12 mutation is significantly associated with the RNA expression of many other genes, with 2,779 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNJ12-associated genes across cancer lineages are MIRLET7BHG, WHAMM, and SLBP. Each is linked with KCNJ12 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNJ12-to-partner and partner-to-KCNJ12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ12→partner) and Y-score (partner→KCNJ12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIRLET7BHG →	+0.689	+2.760	<.001	.002	3	3
UCEC	WHAMM →	+0.503	+1.787	<.001	<.001	3	3
UCEC	SLBP →	+0.450	+2.010	.001	<.001	3	3
UCEC	CACYBP →	+0.439	+1.765	.003	<.001	3	3
COAD	SMU1 →	+0.297	+2.807	.002	.003	3	3
UCEC	UCK1 →	+0.300	+2.161	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,779 associations by consensus.

Exploration

KCNJ12 survival (RNA) · tumor vs normal (RNA) · all KCNJ12 data types