KCNJ12

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KCNJ12 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KCNJ12-associated genes across cancer lineages are STAT3_pY705, ATM, and INPP4B. Each is linked with KCNJ12 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNJ12-to-partner and partner-to-KCNJ12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ12→partner) and Y-score (partner→KCNJ12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSTAT3_pY705 →-0.320-1.514<.001.01533
UCECATM →-0.594-2.523<.001<.00133
COADINPP4B →-0.530-2.313.001.03532
COADRad50 →-0.436-3.450<.001.00532
COADTSC1 →-0.465-3.000<.001.03432
UCECEGFR_pY1068 →-0.247-2.137.003.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration