Across TCGA cell cohorts, KCNJ12 mutation is significantly associated with the RNA expression of many other genes, with 283 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KCNJ12-associated genes across cancer lineages are OR8B8, C1orf94, and KRTAP2-1. Each is linked with KCNJ12 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ12-to-partner and partner-to-KCNJ12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ12→partner) and Y-score (partner→KCNJ12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR8B8 →	+0.016	+2.827	<.001	.004	3	2
LUNG_NSCLC_LUSC	C1orf94 →	+0.018	+2.552	.008	.008	3	1
LUNG_NSCLC_LUSC	KRTAP2-1 →	+0.049	+2.552	.006	.008	3	1
OESOPHAGUS	MARCHF11 →	+0.207	+3.836	.001	.004	3	1
LUNG_SCLC	OR9G4 →	+0.119	+5.029	<.001	.006	3	1
LUNG_SCLC	DEFB123 →	+0.103	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 283 associations by consensus.

Exploration

KCNJ12 survival (RNA) · tumor vs normal (RNA) · all KCNJ12 data types