KCNJ1

Across TCGA patient cohorts, KCNJ1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,325 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCNJ1-associated proteins across cancer lineages are GUCY1B1, MPP1, and ILK. Each is linked with KCNJ1 in more than 4 cancer types. Because this analysis shows association rather than direction, both KCNJ1-to-partner and partner-to-KCNJ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNJ1 versus GUCY1B1 in GBM, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ1→partner) and Y-score (partner→KCNJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GUCY1B1 →	+0.392	+0.234	.004	.006	3	5
GBM	MPP1 →	+0.383	+0.233	.002	.002	2	5
LSCC	ILK →	+0.409	+0.328	<.001	<.001	3	4
LSCC	ARHGAP25 →	+0.565	+0.267	<.001	<.001	3	4
CCRCC	ARHGAP31 →	+0.314	+0.696	<.001	.002	2	5
GBM	ACIN1 →	-0.342	-0.316	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,325 associations by consensus.

KCNJ1 vs GUCY1B1 — GBM

Explore this scatter interactively →