KCNJ1

Across TCGA patient cohorts, KCNJ1 protein abundance is significantly associated with the RNA expression of many other genes, with 185 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible KCNJ1-associated genes across cancer lineages are CLC, RAB5C, and ZC3H7A. Each is linked with KCNJ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KCNJ1-to-partner and partner-to-KCNJ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNJ1 versus CLC in CCRCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNJ1→partner) and Y-score (partner→KCNJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CLC →	+0.806	+0.831	.004	.002	3	1
CCRCC	RAB5C →	+0.397	+1.069	<.001	.003	3	1
CCRCC	ZC3H7A →	-0.403	-1.039	.008	.005	3	1
CCRCC	SLC66A2 →	+0.464	+1.142	<.001	<.001	3	1
CCRCC	NPAS1 →	-0.537	-1.101	.003	.002	3	1
CCRCC	PPAN →	+0.414	+1.016	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 185 associations by consensus.

KCNJ1 vs CLC — CCRCC

Explore this scatter interactively →