KCNIP2

Across TCGA pan-cancer cohorts, KCNIP2 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of KCNIP2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where KCNIP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KCNIP2 is over-expressed in tumor, although a few such as BRCA and HNSC show the opposite, repressed pattern.

KIRC, BRCA, and CHOL are the cancer types where KCNIP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KCNIP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	+0.573	<.001	9	view →
BRCA	All	III,IV	−4.140	<.001	8	view →
CHOL	Female	All	+1.550	<.001	5	view →
HNSC	Male	All	−0.714	.004	4	view →
LIHC	Male	All	+0.162	.010	3	view →
UCEC	All	All	−0.338	.033	2	view →
BLCA	Male	IV	−1.157	.016	1	view →
STAD	All	All	−0.414	.029	1	view →
KICH	All	All	−0.325	.014	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

KCNIP2–KIRC

Open the KIRC breakdown →