KCNIP1-OT1

Across TCGA pan-cancer cohorts, KCNIP1-OT1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated KCNIP1-OT1 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher KCNIP1-OT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KCNIP1-OT1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUAD show a favorable association.

OV, BRCA, and KICH are the cancer types where KCNIP1-OT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	II,III,IV	0.482	0.569	.012	50	view →
BRCA	OS	Median	III,IV	0.657	0.446	.001	48	view →
KICH	OS	Quartile	II,III,IV	0.302	0.905	<.001	45	view →
LUAD	DFS	Median	III,IV	0.602	0.398	.004	44	view →
READ	OS	Quartile	II,III,IV	0.787	0.953	.002	42	view →
ESCA	OS	Tertile	IV	0.143	0.650	.004	36	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
LGG	OS	Tertile	All	0.817	0.952	<.001	23	view →
ACC	OS	Tertile	III,IV	0.189	0.757	<.001	18	view →
KIRP	OS	Median	IV	0.042	0.523	.015	14	view →
SARC	OS	Tertile	All	0.910	0.764	.019	9	view →
LAML	DFS	Quartile	All	0.390	0.720	.028	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

KCNIP1-OT1–OV (DFS)

Open the OV breakdown →