KCNH7-AS1

Across TCGA pan-cancer cohorts, KCNH7-AS1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated KCNH7-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher KCNH7-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KCNH7-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LGG show a favorable association.

KICH, UVM, and COAD are the cancer types where KCNH7-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	II,III,IV	0.274	0.867	<.001	66	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	54	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	45	view →
ESCA	DFS	Tertile	All	0.391	0.573	.010	45	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	45	view →
TGCT	DFS	Tertile	II,III,IV	0.368	0.953	.001	36	view →
HNSC	OS	Tertile	All	0.873	0.737	.019	27	view →
THYM	DFS	Tertile	II,III,IV	0.621	0.933	.009	18	view →
OV	OS	Tertile	IV	0.301	0.764	.038	18	view →
LGG	OS	Tertile	All	0.633	0.371	.011	12	view →
READ	DFS	Tertile	II,III,IV	0.251	0.663	.021	9	view →
SARC	OS	Tertile	All	0.587	0.832	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

KCNH7-AS1–KICH (OS)

Open the KICH breakdown →