KCNH6

Across TCGA cell cohorts, KCNH6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,654 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KCNH6-associated GO terms across cancer lineages are Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Response to epidermal growth factor, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with KCNH6 in more than 5 cancer types. Because this analysis shows association rather than direction, both KCNH6-to-partner and partner-to-KCNH6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay grouped by KCNH6-low versus KCNH6-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH6→partner) and Y-score (partner→KCNH6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.112	+0.159	<.001	.005	3	6
KIDNEY	Response to epidermal growth factor →	+0.102	+0.118	<.001	.008	3	6
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.091	+2.367	<.001	<.001	3	6
KIDNEY	Endoplasmic reticulum to cytosol transport →	+0.113	+0.160	<.001	.001	3	6
KIDNEY	Retrograde protein transport, ER to cytosol →	+0.113	+0.160	<.001	.001	3	6
BLOOD_Leukemia	Host-mediated perturbation of viral process →	+0.031	+0.016	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,654 associations by consensus.

Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay by KCNH6 expression — OESOPHAGUS

Explore this box plot interactively →