KCNH2

Across TCGA patient cohorts, KCNH2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,649 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KCNH2-associated proteins across cancer lineages are SMARCC2, PPP1R13L, and RAD21. Each is linked with KCNH2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNH2-to-partner and partner-to-KCNH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNH2 versus SMARCC2 in UCEC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH2→partner) and Y-score (partner→KCNH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SMARCC2 →	+0.245	+0.859	.004	.005	3	4
HNSC	PPP1R13L →	-0.408	-0.622	<.001	<.001	3	4
HNSC	RAD21 →	+0.213	+0.737	<.001	.005	3	4
LSCC	MYEF2 →	+0.829	+0.982	<.001	<.001	3	4
BRCA	TBC1D2 →	-0.431	-1.342	<.001	<.001	3	4
LSCC	TUBB2B →	+1.361	+0.678	.002	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,649 associations by consensus.

KCNH2 vs SMARCC2 — UCEC

Explore this scatter interactively →