KCNH2

Across TCGA patient cohorts, KCNH2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,366 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KCNH2-associated genes across cancer lineages are SNRPEP2, ZNF330, and KYAT3. Each is linked with KCNH2 in more than 2 cancer types. Because this analysis shows association rather than direction, both KCNH2-to-partner and partner-to-KCNH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNH2 versus SNRPEP2 in OV, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH2→partner) and Y-score (partner→KCNH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SNRPEP2 →	+1.781	+0.981	<.001	<.001	3	3
COAD	ZNF330 →	-0.537	-0.588	.004	.009	3	2
COAD	KYAT3 →	-0.557	-0.664	.007	.002	3	2
COAD	METTL14 →	-0.364	-0.458	.004	.004	3	2
COAD	NDUFS4 →	-0.585	-0.555	.008	.004	3	2
COAD	COPS2 →	-0.717	-0.788	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,366 associations by consensus.

KCNH2 vs SNRPEP2 — OV

Explore this scatter interactively →