KCNH2

Across TCGA patient cohorts, KCNH2 protein abundance is significantly associated with the protein abundance of many other proteins, with 5,999 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KCNH2-associated proteins across cancer lineages are MRPL41, MRPL47, and GTF3C2. Each is linked with KCNH2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KCNH2-to-partner and partner-to-KCNH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KCNH2 versus MRPL41 in BRCA, with a Pearson correlation of 0.87.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KCNH2→partner) and Y-score (partner→KCNH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MRPL41 →	+1.288	+2.469	<.001	.003	3	4
BRCA	MRPL47 →	+0.674	+1.639	<.001	<.001	3	3
PDAC	GTF3C2 →	+0.238	+0.526	<.001	<.001	3	2
PDAC	ARHGEF17_S79 →	-0.804	-0.674	<.001	<.001	3	2
OV	CEP131_S78 →	+0.875	+0.850	<.001	<.001	3	2
BRCA	FER →	-0.829	-2.278	.004	.007	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,999 associations by consensus.

KCNH2 vs MRPL41 — BRCA

Explore this scatter interactively →